Eastern's enrollment grew rapidly in the post-World War II years, resulting in high demand for campus housing. Construction plans called for four buildings surrounding a central dining facility. When completed, the new housing would contain space for approximately 1,200 students in the center of campus. The new housing was originally intended for women, and builders hoped to complete the complex by 1958. Downing opened first in 1957, followed by Buell in 1958, then Wise and Best opened in the 1960s. Wise was able to house 322 students and included meeting rooms, laundry facilities, and recreational areas. Wise Hall received an $11.5 million renovation in 2016, receiving necessary modern updates including installation of A/C units and Wi-Fi. Wise still serves as a residence hall for undergraduate students.
Additionally, the Brotherhood and Sisterhood Scholars Programs are housed in Wise. These programs are designed to increase retention and graduation rates for students identifying as people of color. Through collaborative university partnerships, the Brotherhood and Sisterhood Scholars programs guide students in their transition to college by providing an extended orientation, a residential community, designated courses, mentorship and workshops.